1. Shrew submaxillary gland epidermal growth factor: homologous radioreceptor assay and mitogenic activity.

Yip TT[1], Tsao SW[2], Ko KM[1], Xin JX[3], Kong YC[1,3].

[1] Department of Biochemistry, The Chinese University of Hong Kong, Shatin, Hong Kong.
[2] Department of Anatomy, The Chinese University of Hong Kong, Shatin, Hong Kong.
[3] Department of Biology, Zhongshan University, Guangzhou, China.

A homologous radioreceptor assay was developed to determine the epidermal growth factor (EGF) contents of the shrew submaxillary glands. The results supported previous findings by heterologous radioreceptor assay that this gland in the shrew contained a high level of EGF. This EGF was also found to be a powerful mitogen in two fibroblast cell lines.